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Article

Mechanism of action of diazaborines.

Biochemical pharmacology - 15 May 1998

Baldock C, de Boer G J, Rafferty J B, Stuitje A R, Rice D W

Abstract excerpt

The diazaborine family of compounds have antibacterial properties against a range of gram-negative bacteria. Initially, this was thought to be due to the prevention of lipopolysaccharide synthesis. More recently, the molecular target of diazaborines has been identified as the NAD(P)H-dependent enoyl acyl carrier protein reductase (ENR), which catalyses the last reductive step of fatty acid synthase. ENR from...

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PMID: 9633989
DOI: 10.1016/s0006-2952(97)00684-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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