Article
The Functional Model Complex [Fe<sub>2</sub>(BPMP)(OPr)(NO)<sub>2</sub>](BPh<sub>4</sub>)<sub>2</sub> Provides Insight into the Mechanism of Flavodiiron NO Reductases
10 Mar 2013
Abstract excerpt
Flavodiiron nitric oxide reductases (FNORs), found in many pathogenic bacteria, are able to detoxify NO by reducing it to N2O. In this way, FNORs equip these pathogens with immunity to NO, which is a central immune defense agent in humans. Hence, FNORs are thought to promote infection of the human body, leading to chronic diseases. Despite this importance of FNORs for bacterial pathogenesis, the mechanism of NO...
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