Article
Clinical features associated with the homozygous Trp64Arg mutation of the beta3-adrenergic receptor: no evidence for its association with obesity in Japanese.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 1998
Sun L, Ishibashi S, Osuga J, Harada K, Ohashi K, Gotoda T, Fukuo Y, Yazaki Y, Yamada N
Abstract excerpt
To characterize the clinical features associated with the Trp64Arg mutation of the beta3-adrenergic receptor (beta3-AR), the effects of this mutation, in particular the homozygous state (Arg/Arg), on obesity, blood pressure, and plasma lipoproteins were investigated in 2 populations: subjects res...
Topics
- Arginine
- Blood Pressure
- Body Mass Index
- Cholesterol, LDL
- Cohort Studies
- Diabetes Mellitus, Type 2
- Electrocardiography
- Female
- Gene Frequency
- Genotype
- Humans
- Japan
- Male
- Middle Aged
- Obesity