Article
A mutation of the beta 3-adrenergic receptor is associated with visceral obesity but decreased serum triglyceride.
Diabetologia - 1 Apr 1997
Kim-Motoyama H, Yasuda K, Yamaguchi T, Yamada N, Katakura T, Shuldiner A R, Akanuma Y, Ohashi Y, Yazaki Y, Kadowaki T
Abstract excerpt
The Trp64Arg mutation of the beta 3-adrenergic receptor (beta 3AR) is prevalent in several ethnic groups and is associated with weight gain, and some features of syndrome X such as insulin resistance and dyslipidaemia. Nevertheless, it is not known at present whether this mutation is associated with visceral obesity, which is an important risk factor for the development of hypertension, dyslipidaemia, insulin...
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