Article
A mutation of the beta 3-adrenergic receptor is associated with visceral obesity but decreased serum triglyceride.
Diabetologia - 1 Apr 1997
Kim-Motoyama H, Yasuda K, Yamaguchi T, Yamada N, Katakura T, Shuldiner A R, Akanuma Y, Ohashi Y, Yazaki Y, Kadowaki T
Abstract excerpt
The Trp64Arg mutation of the beta 3-adrenergic receptor (beta 3AR) is prevalent in several ethnic groups and is associated with weight gain, and some features of syndrome X such as insulin resistance and dyslipidaemia. Nevertheless, it is not known at present whether this mutation is associated w...
Topics
- Adult
- Aged
- Alleles
- Arginine
- Body Mass Index
- Cholesterol
- Deoxyribonucleases, Type II Site-Specific
- Diabetes Mellitus, Type 2
- Genotype
- Glucose Intolerance
- Heterozygote
- Homozygote
- Humans
- Insulin
- Male
- Middle Aged
- Obesity
- Phenotype