Article
Association of beta3-adrenergic receptor gene polymorphism with insulin resistance in Japanese-American men.
Metabolism: clinical and experimental - 1 Nov 1999
Kawamura T, Egusa G, Okubo M, Imazu M, Yamakido M
Abstract excerpt
The Trp64Arg variant of the beta3-adrenergic receptor (beta3-AR) gene is relatively common in Japanese people. We hypothesized that this variant may be associated with obesity and insulin resistance when combined with a westernized lifestyle. To test this hypothesis, we investigated the relationships between the beta3-AR gene variant and obesity and insulin resistance in Japanese-American men, who are known to...
Topics
- Adult
- Aged
- Alleles
- Asian
- Asian People
- Body Mass Index
- Genotype
- Glucose Tolerance Test
- Hawaii
- Humans
- Insulin Resistance
- Male
- Middle Aged
- Obesity
- Polymorphism, Genetic
- Receptors, Adrenergic, beta
- Receptors, Adrenergic, beta-3
