Article
Prevalence of the Trp64Arg missense mutation of the beta3-adrenergic receptor gene in Japanese subjects.
Metabolism: clinical and experimental - 1 Feb 1997
Ueda K, Tanizawa Y, Oota Y, Inoue H, Kizuki N, Inoue H, Tsukuda K, Asano T, Oka Y
Abstract excerpt
Prompted by the recent findings that a tryptophan to arginine (Trp64Arg) mutation in the beta3-adrenergic receptor gene was associated with an earlier onset of non-insulin-dependent diabetes mellitus (NIDDM) in Pima Indians, with abdominal obesity and insulin resistance in Finns, and with an increased capacity to gain weight in French whites, we studied the prevalence of this mutation in 231 diabetic and 95...
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