Association of CYP2D microsatellite polymorphism with Lewy body variant of Alzheimer's disease.

doi:10.1212/wnl.50.6.1556

Article

Association of CYP2D microsatellite polymorphism with Lewy body variant of Alzheimer's disease.

Neurology - 1 Jun 1998

Tanaka S, Chen X, Xia Y, Kang D E, Matoh N, Sundsmo M, Thomas R G, Katzman R, Thal L J, Trojanowski J Q, Saitoh T, Ueda K, Masliah E

Abstract excerpt

OBJECTIVE: To examine the genetic association of CYP2D6 locus with Lewy body variant (LBV) and Parkinson's disease (PD). METHODS: Allelic association was studied in patients with pure AD, LBV, and PD by using the CYP2D microsatellite, the (dG-dT)n dinucleotide repeat (n=16 to 27) located between...

Topics

Aged
Alleles
Alzheimer Disease
Cytochrome P-450 CYP2D6
Genotype
Humans
Microsatellite Repeats
Mutation
Parkinson Disease
Polymorphism, Genetic

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