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Article

CYP2D6 gene polymorphism as a probable risk factor for Alzheimer's disease and Parkinson's disease with dementia.

Neurologia i neurochirurgia polska - 1 Jan 2000

Gołab-Janowska Monika, Honczarenko Krystyna, Gawrońska-Szklarz Barbara, Potemkowski Andrzej

Abstract excerpt

BACKGROUND AND PURPOSE: The theory of multifactorial inheritance is considered in the pathogenesis of sporadic Alzheimer's disease (AD) and Parkinson's disease (PD); therefore, it makes the genes regulating bioactivation or detoxification of exogenous substances candidates of sensitivity to Alzheimer's and Parkinson's diseases. The aims of the study were: 1) to determine the genotypes of CYP2D6 cytochrome...

Topics

Aged
Aged, 80 and over
Alzheimer Disease
Antiparkinson Agents
Cytochrome P-450 CYP2D6
Dementia
Female
Genetic Predisposition to Disease
Humans
Levodopa
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Parkinson Disease

Polymorphism, Genetic

Risk Factors

Severity of Illness Index

Source

Identifiers

PMID: 17530572

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CYP2D6 gene polymorphism as a probable risk factor for Alzheimer's disease and Parkinson's disease with dementia.PMID 17530572Read ↗

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