Article
Association of monoamine oxidase A gene polymorphism with Alzheimer's disease and Lewy body variant.
Neuroscience letters - 19 Jul 2002
Takehashi Masanori, Tanaka Seigo, Masliah Eliezer, Ueda Kunihiro
Abstract excerpt
The association between (GT)n dinucleotide repeats in monoamine oxidase gene loci, monoamine oxidase A (MAOA) and B (MAOB), and Parkinson's disease (PD), Alzheimer's disease (AD), and Lewy body variant (LBV) of AD were determined. MAOA-GT polymorphisms were significantly associated with pure AD and LBV. MAOA-GT allele 113 was excessively represented in pure AD and LBV compared with controls. Furthermore, the...
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