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Article

Neurogenetic correlates of Parkinson's disease: apolipoprotein-E and cytochrome P450 2D6 genetic polymorphism.

Neuroscience letters - 7 May 1999

Bon M A, Jansen Steur E N, de Vos R A, Vermes I

Abstract excerpt

Brain tissue of 50 patients with morphological confirmed Parkinson's disease (PD), blood samples from 149 patients with clinical parkinsonism and from 96 healthy control subjects were collected. Apolipoprotein-E (apo E) and cytochrome P450 2D6 (CYP2D6) genotyping were performed by PCR followed by restriction fragment analysis. A significantly higher allele frequency of CYP2D6*4 was found in patients with PD (35%)...

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Source

Identifiers

PMID: 10353349
DOI: 10.1016/s0304-3940(99)00278-5

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Source receipt: pubmed, retrieved 7 Sept 2026.

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