Article
Population analysis of the collagen type IIalpha1 3' variable number of tandem repeat polymorphism by heteroduplex genotyping.
Electrophoresis - 1 May 1998
Uitterlinden A G, Huang Q, Pols H A, van Leeuwen J P
Abstract excerpt
The AT-rich variable number of tandem repeat (VNTR) marker at the 3' end of the collagen type IIalpha1 (COL2A1) gene has been shown to have a complex structure with extensive sequence variations among repeat units. We analyzed this VNTR polymorphism in a large population of 972 Caucasian individu...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Collagen
- Electrophoresis, Polyacrylamide Gel
- Female
- Gene Frequency
- Genotype
- Humans
- Male
- Middle Aged
- Nucleic Acid Heteroduplexes
