Article
Population analysis of the collagen type IIalpha1 3' variable number of tandem repeat polymorphism by heteroduplex genotyping.
Electrophoresis - 1 May 1998
Uitterlinden A G, Huang Q, Pols H A, van Leeuwen J P
Abstract excerpt
The AT-rich variable number of tandem repeat (VNTR) marker at the 3' end of the collagen type IIalpha1 (COL2A1) gene has been shown to have a complex structure with extensive sequence variations among repeat units. We analyzed this VNTR polymorphism in a large population of 972 Caucasian individuals with a genotyping procedure involving heteroduplex analysis of PCR products using polyacrylamide gel...
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