Population genetics of hypervariable loci: analysis of PCR based VNTR polymorphism within a population.

doi:10.1007/978-3-0348-7312-3_10

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Article

Population genetics of hypervariable loci: analysis of PCR based VNTR polymorphism within a population.

EXS - 1 Jan 1991

Chakraborty R, Fornage M, Gueguen R, Boerwinkle E

Abstract excerpt

Using a polymerase chain reaction (PCR) based method, genotypes at two hypervariable loci (3' to the Apo-B-structural gene and at the ApoC-II gene) were determined by size classification of alleles. Genotype data at the Apo-B locus (Apo-B VNTR) were obtained on 240 French Caucasians; the sample s...

Topics

Alleles
Apolipoprotein C-II
Apolipoproteins B
Apolipoproteins C
DNA, Satellite
Gene Frequency
Genetics, Population
Genotype
Heterozygote
Humans
Mutation
Polymerase Chain Reaction
Polymorphism, Genetic
Random Allocation

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