Article
Sequence variants in the human cocaine and amphetamine-regulated transcript (CART) gene in subjects with early onset obesity.
Obesity research - 1 Nov 1999
Echwald S M, Sørensen T I, Andersen T, Hansen C, Tommerup N, Pedersen O
Abstract excerpt
OBJECTIVE: The cocaine and amphetamine-regulated transcript (CART) is expressed in the brain of rodents and humans, and intracerebroventricular injection of the peptide in rats reduces food intake. The objective of the present study was to chromosomally map the CART gene and to examine the coding region of the gene for variability in obese subjects. METHODS: The coding region of the CART gene was analyzed by...
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