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Article

Association between a null mutation in the human ciliary neurotrophic factor (CNTF) gene and increased incidence of psychiatric diseases?

Neuroscience letters - 19 Jan 1996

Thome J, Kornhuber J, Baumer A, Rösler M, Beckmann H, Riederer P

Abstract excerpt

We report a possible association between a null mutation in the human ciliary neurotrophic factor (CNTF) gene and psychiatric diseases. Prior findings that the mutant allele frequency is not significantly elevated in patients suffering from neurological diseases are confirmed. The frequency of the mutant allele was higher among psychiatric patients (0.192, n = 297) than among healthy controls and neurological...

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Source

Identifiers

PMID: 8834105
DOI: 10.1016/0304-3940(95)12274-5

Genes

CNTF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Association between a null mutation in the human ciliary neurotrophic factor (CNTF) gene and increased incidence of psychiatric diseases?PMID 8834105Read ↗

A null mutation in the human CNTF gene is not causally related to neurological diseases.Semantic proximity Read ↗

Schizophrenia and the ciliary neurotrophic factor (CNTF) gene: no evidence for association.Semantic proximity Read ↗

Schizophrenic psychoses and the CNTF null mutation.Semantic proximity Read ↗

Ciliary neurotrophic factor null mutation and schizophrenia in a Swedish population.Semantic proximity Read ↗

A null mutation allele in the CNTF gene and schizophrenic psychoses.Semantic proximity Read ↗

No association between the CNTF null mutation and schizophrenia or personality.Semantic proximity Read ↗

Variants in neurotrophic factor genes and schizophrenic psychoses: no associations in a Spanish population.Semantic proximity Read ↗

Ciliary neurotrophic factor null allele frequencies in schizophrenia, affective disorders, and Alzheimer's disease.Semantic proximity Read ↗

Ciliary neurotrophic factor (CNTF) genotypes: influence on choline acetyltransferase (ChAT) and acetylcholine esterase (AChE) activities and neurotrophin 3 (NT3) concentration in human post mortem brain tissue.Semantic proximity Read ↗

Association study of BDNF and CNTF polymorphism to depression in non-demented subjects of the "VITA" study.Semantic proximity Read ↗

[Deficiency of human ciliary neurotropic factor (CNTF) is not causally related to amyotrophic lateral sclerosis (ALS)].Semantic proximity Read ↗

[Brain-derived neurotrophic factor and psychiatric diseases].Semantic proximity Read ↗

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