Gene trap integrations expressed in the developing heart: insertion site affects splicing of the PT1-ATG vector.

doi:10.1002/(SICI)1097-0177(199806)212:2<267::AID-AJA11>3.0.CO;2-1

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Gene trap integrations expressed in the developing heart: insertion site affects splicing of the PT1-ATG vector.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 1998

McClive P, Pall G, Newton K, Lee M, Mullins J, Forrester L

Abstract excerpt

We describe the characterisation of three gene trap integrations in embryonic stem cells in which the lacZ reporter gene is repressed by retinoic acid (RA) in vitro and is expressed in the developing heart in vivo. In one of these, the gene trap vector has integrated into a gene that is located o...

Topics

Animals
Artificial Gene Fusion
Base Sequence
Chromosome Mapping
DNA, Complementary
Embryonic and Fetal Development
Exons
Female
Fetal Heart
Genes, Reporter
Genetic Techniques
Genetic Vectors
Heart Defects, Congenital
Humans
Lac Operon
Male
Mice
Mice, Inbred C57BL

Source

Open in PubMed

Identifiers

PMID: 9626501
DOI: 10.1002/(SICI)1097-0177(199806)212:2<267::AID-AJA11>3.0.CO;2-1

Genes

TFEB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9626501-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics