Article
A gene trap integration provides an early in situ marker for hepatic specification of the foregut endoderm.
Mechanisms of development - 1 Feb 2001
Watt A J, Jones E A, Ure J M, Peddie D, Wilson D I, Forrester L M
Abstract excerpt
We report the characterization of a gene trap integration that provides an in situ marker for one of the earliest events in liver development. Expression of the reporter gene is observed at the nine-somite stage in the hepatic field of the foregut endoderm. At 10.5 days post-coitus expression is observed exclusively and at high levels in the majority of cells in the developing liver bud. As development proceeds...
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