Article
Variable expression of the V1 vasopressin receptor modulates the phenotypic response of steroid-secreting adrenocortical tumors.
The Journal of clinical endocrinology and metabolism - 1 Jun 1998
Arnaldi G, Gasc J M, de Keyzer Y, Raffin-Sanson M L, Perraudin V, Kuhn J M, Raux-Demay M C, Luton J P, Clauser E, Bertagna X
Abstract excerpt
We studied the putative role of the vasopressin receptors in the phenotypic response of steroid-secreting adrenocortical tumors. A retrospective analysis of a series of 26 adrenocortical tumors responsible for Cushing's syndrome (19 adenomas and 7 carcinomas) showed that vasopressin (10 IU, i.m., lysine vasopressin) induced an ACTH-independent cortisol response (arbitrarily defined as a cortisol rise above...
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