Article
Variable expression of the V1 vasopressin receptor modulates the phenotypic response of steroid-secreting adrenocortical tumors.
The Journal of clinical endocrinology and metabolism - 1 Jun 1998
Arnaldi G, Gasc J M, de Keyzer Y, Raffin-Sanson M L, Perraudin V, Kuhn J M, Raux-Demay M C, Luton J P, Clauser E, Bertagna X
Abstract excerpt
We studied the putative role of the vasopressin receptors in the phenotypic response of steroid-secreting adrenocortical tumors. A retrospective analysis of a series of 26 adrenocortical tumors responsible for Cushing's syndrome (19 adenomas and 7 carcinomas) showed that vasopressin (10 IU, i.m.,...
Topics
- Adenoma
- Adrenal Cortex Hormones
- Adrenal Cortex Neoplasms
- Carcinoma
- Cushing Syndrome
- Gene Expression
- Humans
- Hydrocortisone
- In Situ Hybridization
- Lypressin
- Phenotype
- Polymerase Chain Reaction
- RNA, Messenger
- RNA-Directed DNA Polymerase