Article
V3 vasopressin receptor and corticotropic phenotype in pituitary and nonpituitary tumors.
Hormone research - 1 Jan 1997
de Keyzer Y, René P, Lenne F, Auzan C, Clauser E, Bertagna X
Abstract excerpt
Pituitary corticotropic cells express a specific vasopressin receptor, called V1b or V3, through which vasopressin stimulates corticotropin secretion. We recently cloned a cDNA coding for this receptor and showed that it belongs to the G protein-coupled receptor family. V3 mRNA is readily detected by RT-PCR in normal human pituitaries and corticotropic pituitary adenomas but not in PRL or GH-secreting adenomas,...
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