[Membrane receptors and endocrine tumors: expression of vasopressin receptor V1 modulates the pharmacologic phenotype of adrenocortical tumors].

Article

[Membrane receptors and endocrine tumors: expression of vasopressin receptor V1 modulates the pharmacologic phenotype of adrenocortical tumors].

Bulletin de l'Academie nationale de medecine - 1 Jan 1998

Luton J P, Bertagna X

Abstract excerpt

A retrospective analysis of 26 adrenocortical tumors responsible for Cushing's syndrome showed that vasopressin induced an ACTH-independent cortisol response in seven cases (27%). In comparison 68 of 90 patients with Cushing's disease (76%) had a positive cortisol response. The mRNA for the V1-ty...

Topics

Adrenal Gland Neoplasms
Endocrine Gland Neoplasms
Humans
Phenotype
Receptors, Vasopressin
Retrospective Studies

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