Article
The pituitary V3 vasopressin receptor and the corticotroph phenotype in ectopic ACTH syndrome.
The Journal of clinical investigation - 1 Mar 1996
de Keyzer Y, Lenne F, Auzan C, Jégou S, René P, Vaudry H, Kuhn J M, Luton J P, Clauser E, Bertagna X
Abstract excerpt
Ectopic ACTH secretion occurs in highly differentiated and rather indolent tumors like bronchial carcinoids or, in contrast, in various types of aggressive and poorly differentiated neuroendocrine tumors. We explored this phenomenon using the recently cloned human pituitary V3 vasopressin receptor as an alternate molecular marker of the corticotroph phenotype. Expression of V3 receptor, corticotrophin releasing...
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