Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The host reaction to toxic agents.

Annals of clinical and laboratory science - 1 Jan 2000

Rennert O M

Abstract excerpt

The identification of side effects of chemotherapeutic and environmental agents has assumed a central role in current day medical practice. Since 1962, the formal recognition of the functional role of host factors in drug idiosyncrasies has resulted in the delineation of the discipline of pharmacogenetics. This investigative arena deals with inborn errors of metabolism which affect drug metabolizing enzymes or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotype
Share to Age Factors
Share to Carcinogens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetics

Share to Isoniazid

Share to Metabolism, Inborn Errors

Share to Mixed Function Oxygenases

Share to Sex Factors

Source

Identifiers

PMID: 962293

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The host reaction to toxic agents.PMID 962293Read ↗

Epidemiology and individual susceptibility to adverse drug reactions affecting the liver.Semantic proximity Read ↗

Analysis of drug-protein adducts and their role in drug hypersensitivitySemantic proximity Read ↗

Liver injury caused by drugs: an update.Semantic proximity Read ↗

Mechanisms of drug-induced liver injurySemantic proximity Read ↗

"Host factors"--evolution of concepts of individual sensitivity and susceptibility.Semantic proximity Read ↗

Anticonvulsant hypersensitivity syndrome: a review.Semantic proximity Read ↗

<i>In vitro</i>analysis of metabolic predisposition to drug hypersensitivity reactionsSemantic proximity Read ↗

Definition of antigenic determinants in drug hypersensitive patients : an integrated clinical, chemical and cellular approach to quantify and characterize the drug signals presented to T-LymphocytesSemantic proximity Read ↗

Mechanisms of idiosyncratic hypersensitivity reactions to antiepileptic drugs.Semantic proximity Read ↗

Mechanisms in pulmonary toxicology.Semantic proximity Read ↗

Investigation of Oxidative Stress-Related Candidate Genes as Risk Factors for Drug-Induced Liver Injury due to Co-Amoxiclav.Semantic proximity Read ↗

Phenotypic variation in xenobiotic metabolism and adverse environmental response: focus on sulfur-dependent detoxification pathways.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.