Article
"Host factors"--evolution of concepts of individual sensitivity and susceptibility.
International journal of hygiene and environmental health - 1 Oct 2001
Hoffmann W, Oberheitmann B, Frentzel-Beyme R
Abstract excerpt
The detection of a rapidly increasing number of genetic polymorphisms in xenogen-metabolizing enzymes, of hereditary as well as acquired individual differences in DNA repair, and of the close associations between central nervous structures, the endocrine, and the immune system provides a challenge to develop an evidence-based, comprehensive model of susceptibility. Reviewing the evolution of respective approaches...
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