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Article

Endothelial cell modulation of smooth muscle cell morphology and organizational growth pattern.

Annals of vascular surgery - 1 Jan 1996

Powell R J, Cronenwett J L, Fillinger M F, Wagner R J, Sampson L N

Abstract excerpt

Intimal hyperplasia is characterized by smooth muscle cell (SMC) dedifferentiation from a contractile to a synthetic phenotype prior to migration and proliferation. Regulatory mechanisms controlling SMC phenotype are not well known. This study examined the effect of endothelial cells (ECs) on SMC morphology in coculture. Subcultured bovine ECs and SMCs were plated on opposite sides of a 13 microns thick,...

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PMID: 8688295
DOI: 10.1007/BF02002334

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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