Article
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons.
Nature genetics - 1 Jun 1998
Parkes T L, Elia A J, Dickinson D, Hilliker A J, Phillips J P, Boulianne G L
Abstract excerpt
Reactive oxygen (RO) has been identified as an important effector in ageing and lifespan determination. The specific cell types, however, in which oxidative damage acts to limit lifespan of the whole organism have not been explicitly identified. The association between mutations in the gene encod...
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