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Article

Lessons from models of SOD1-linked familial ALS.

Trends in molecular medicine - 1 Aug 2004

Bendotti Caterina, Carrì Maria Teresa

Abstract excerpt

Ten years ago, the linkage between mutations in the gene coding for the antioxidant enzyme Cu,Zn superoxide dismutase (SOD1) and the neurodegenerative disease known as familial amyotrophic lateral sclerosis (FALS) was established. This finding has prompted a myriad of new studies in experimental models aimed at investigating the toxic function of the mutant enzymes. The cellular functions that are impaired in...

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Identifiers

PMID: 15310460
DOI: 10.1016/j.molmed.2004.06.009

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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