Article
Intermediate alpha 1-antitrypsin deficiency PiSZ: a risk factor for pulmonary emphysema?
Respiratory medicine - 1 Feb 1998
Seersholm N, Kok-Jensen A
Abstract excerpt
It is well documented that the severe hereditary disorder alpha 1-antitrypsin deficiency (alpha 1ATD) PiZZ is a strong risk factor for emphysema, especially among smokers, but the role of intermediate alpha 1ATD PiMZ and PiSZ in the development of emphysema remains uncertain. In this study, we have evaluated mortality and lung function of 94 persons with intermediate alpha 1ATD PiSZ of whom 66 were non-index...
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