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Article

[PIS and PIZ alpha 1-antitrypsin deficiency: estimated prevalence and number of deficient subjects in Spain].

Medicina clinica - 4 Dec 2004

Blanco Ignacio, Fernández-Bustillo Enrique, de Serres Frederick J, Alkassam Daniel, Rodríguez Menéndez Carmen

Abstract excerpt

BACKGROUND AND OBJECTIVE: Alpha-1-antitrypsin deficiency (AATD) is an hereditary disorder with increased risk of pulmonary emphysema and chronic liver diseases in children and adults. Since it is possible currently in Spain to apply alpha-1-antitrypsin replacement therapy to AATD patients, the objective of this study was to calculate the total number of subjects affected by PIS and PIZ AATD, and its phenotypic...

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Identifiers

PMID: 15607066
DOI: 10.1016/s0025-7753(04)74661-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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