Analysis of complement receptor type 1 (CR1) expression on erythrocytes and of CR1 allelic markers in Caucasian and African American populations.

doi:10.1006/clin.1998.4529

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Article

Analysis of complement receptor type 1 (CR1) expression on erythrocytes and of CR1 allelic markers in Caucasian and African American populations.

Clinical immunology and immunopathology - 1 May 1998

Herrera A H, Xiang L, Martin S G, Lewis J, Wilson J G

Abstract excerpt

CR1 expression on erythrocytes (E) is regulated by an element that is tightly linked in Caucasians to the site of an RFLP of the CR1 gene. Genomic HindIII fragments of 7.4 and 6.9 kb identify alleles that are expressed in high (H allele) or low (L allele) amounts, respectively. When age-fractionated E of donors heterozygous for both the H and L alleles and for CR1 allotypes of differing molecular weights were...

Topics

Alleles
Black People
Blotting, Western
Erythrocytes
Genetic Markers
Genotype
Humans
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Receptors, Complement 3b
White People
Black or African American

Source

Open in PubMed

Identifiers

PMID: 9614933
DOI: 10.1006/clin.1998.4529

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