Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative alleles of CR1: coding sequence analysis and comparison of haplotypes in two ethnic groups.

Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 1999

Xiang L, Rundles J R, Hamilton D R, Wilson J G

Abstract excerpt

The quantitative expression of complement receptor type 1 (CR1) on erythrocytes is regulated by two CR1 alleles that differ in having genomic HindIII fragments of either 7.4 or 6.9 kb and that determine high (H allele) or low (L allele) CR1 expression, respectively, across a 10-fold range. To investigate whether the product of the L allele may contain amino acid substitutions that make it more susceptible to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Black or African American

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Black People

Share to Haplotypes

Share to Polymorphism, Restriction Fragment Length

Share to Receptors, Complement 3b

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to White People

Source

Identifiers

PMID: 10528197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative alleles of CR1: coding sequence analysis and comparison of haplotypes in two ethnic groups.PMID 10528197Read ↗

Analysis of complement receptor type 1 (CR1) expression on erythrocytes and of CR1 allelic markers in Caucasian and African American populations.Semantic proximity Read ↗

Erythrocyte CR1 expression level does not correlate with a HindIII restriction fragment length polymorphism in Africans; implications for studies on malaria susceptibility.Semantic proximity Read ↗

Erythrocyte complement receptor 1 (CR1) expression level is not associated with polymorphisms in the promoter or 3' untranslated regions of the CR1 gene.Semantic proximity Read ↗

A complement receptor-1 polymorphism with high frequency in malaria endemic regions of Asia but not Africa.Semantic proximity Read ↗

CR1 levels and gene polymorphisms exhibit differential association with falciparum malaria in regions of varying disease endemicity.Semantic proximity Read ↗

Structural polymorphisms of complement receptor 1 (CR1) in systemic lupus erythematosus (SLE) patients and normal controls of three ethnic groups.Semantic proximity Read ↗

A CR1 polymorphism associated with constitutive erythrocyte CR1 levels affects binding to C4b but not C3b.Semantic proximity Read ↗

Proposed structure of the F' allotype of human CR1. Loss of a C3b binding site may be associated with altered function.Semantic proximity Read ↗

Genomic determination of the CR1 (CD35) density polymorphism on erythrocytes using polymerase chain reaction amplification and HindIII restriction enzyme digestionSemantic proximity Read ↗

Structure of the gene for the F allele of complement receptor type 1 and sequence of the coding region unique to the S allele.Semantic proximity Read ↗

Inherited and Acquired Decrease in Complement Receptor 1 (CR1) Density on Red Blood Cells Associated with High Levels of Soluble CR1 in Alzheimer's Disease.Semantic proximity Read ↗

Genetic and structural polymorphism of complement receptor 1 in normal Indian subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.