Article
The new collagen gene COL27A1 contains SOX9-responsive enhancer elements.
Matrix biology : journal of the International Society for Matrix Biology - 1 May 2005
Jenkins Elizabeth, Moss Jennie B, Pace James M, Bridgewater Laura C
Abstract excerpt
The most recently discovered collagen gene, COL27A1, codes for type XXVII collagen. The COL27A1 gene is strongly expressed in developing cartilage and weakly expressed in many other tissue types. The present study was undertaken to identify transcriptional regulatory mechanisms that govern the expression of COL27A1 in cartilage, and in particular to determine whether SOX9, a key regulator of chondrogenesis, could...
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