Article

Regulation of Human COL2A1 Gene Expression in Chondrocytes

2000-09-01

Abstract excerpt

To identify control motifs involved in human type II collagen gene transcription in both differentiated and dedifferentiated rabbit articular chondrocytes, transient transfection experiments were performed. A 715-base pair (bp) region of the first intron (+2127/+2842), including a 153-bp sequence so far uncharacterized (+2689/+2842), was found to mediate enhancer activity. In dedifferentiated chondrocytes, this en...

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Literature Corpus work: cc000a84-91eb-5998-9244-4398498d5cdb
DOI: 10.1016/s0021-9258(19)61527-9

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