Article
IL-3-mediated enhancement of particulate antigen presentation by macrophages.
Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 May 1998
Lord E M, Yeh K Y, Moran J A, Storozynsky E, Frelinger J G
Abstract excerpt
Mice were exposed to interleukin- (IL-) 3 in vivo by injection of tumor cells transfected with the IL-3 gene. At 10 days post tumor injection, bone marrow cells were recovered, pulsed with particulate antigen in the form of ovalbumin (Ova)-coated magnetic beads, and tested for their ability to present antigen via class I to an Ova/class I-restricted T cell hybridoma. Cells from IL-3-stimulated mice exhibited a...
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