Functional analysis of the p53 protein in AIDS-related non-Hodgkin's lymphomas and polymorphic lymphoproliferations.

doi:10.1046/j.1365-2141.1998.00692.x

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Article

Functional analysis of the p53 protein in AIDS-related non-Hodgkin's lymphomas and polymorphic lymphoproliferations.

British journal of haematology - 1 May 1998

Martin A, Flaman J M, Frebourg T, Davi F, El Mansouri S, Amouroux J, Raphaël M

Abstract excerpt

Alteration of the tumour suppressor gene p53 is frequent in AIDS-related non-Hodgkin's lymphomas (AIDS-NHL), particularly in Burkitt's or Burkitt's-like lymphomas (BL/BLL). Since mechanisms of inactivation other than mutations have been advanced, the transcriptional activity of the p53 protein wa...

Topics

Cell Division
Gene Rearrangement
Genes, myc
Genes, p53
Humans
Lymphocyte Activation
Lymphoma, AIDS-Related
Mutation
Tumor Suppressor Protein p53

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