Article
Mutation and protein expression of p53 in acquired immunodeficiency syndrome-related lymphomas.
Blood - 1 Aug 1993
Nakamura H, Said J W, Miller C W, Koeffler H P
Abstract excerpt
p53 mutations are found in a variety of neoplasia. B-immunoblastic lymphoma (BIBL) is a rapidly progressive, aggressive lymphoma. As patients with acquired immunodeficiency syndrome (AIDS) live longer, BIBL is becoming an increasing problem. We asked three questions in our study. What is the frequency of p53 mutations in BIBL? Is it more frequent in patients with AIDS? Can immunohistochemical staining of lymph...
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