Article
Calreticulin and calnexin interact with different protein and glycan determinants during the assembly of MHC class I.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 1998
Harris M R, Yu Y Y, Kindle C S, Hansen T H, Solheim J C
Abstract excerpt
Before peptide binding, a variety of endoplasmic reticulum (ER) proteins are associated with class I including calnexin, TAP, calreticulin, and tapasin. Although the selective functions of any one of these ER proteins have been difficult to define, individually or in combination they perform two...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP-Binding Cassette Transporters
- Amino Acid Substitution
- Animals
- Antiporters
- Calcium-Binding Proteins
- Calnexin
- Calreticulin
- Carbohydrate Conformation
- Epitopes
- Histocompatibility Antigens Class I
- Humans
- Immunoglobulins
- L Cells
- Membrane Transport Proteins
- Mice
- Mice, Inbred C57BL
- Mutation