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Article

Contribution of tryptophan residues to the structural changes in perfringolysin O during interaction with liposomal membranes.

Journal of biochemistry - 1 Jun 1998

Nakamura M, Sekino-Suzuki N, Mitsui K, Ohno-Iwashita Y

Abstract excerpt

Perfringolysin O (theta-toxin) is a cholesterol-binding and pore-forming toxin that shares with other thiol-activated cytolysins a highly conserved sequence, ECTGLAWEWWR (residues 430-440), near the C-terminus. To understand the membrane-insertion and pore-forming mechanisms of the toxin, we evaluated the contribution of each Trp to the toxin conformation during its interaction with liposomal membranes. Circular...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9604004
DOI: 10.1093/oxfordjournals.jbchem.a022054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Contribution of tryptophan residues to the structural changes in perfringolysin O during interaction with liposomal membranes.PMID 9604004Read ↗

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