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Article

Identification of rat susceptibility loci for adjuvant-oil-induced arthritis.

Proceedings of the National Academy of Sciences of the United States of America - 26 May 1998

Lorentzen J C, Glaser A, Jacobsson L, Galli J, Fakhrai-rad H, Klareskog L, Luthman H

Abstract excerpt

One intradermal injection of incomplete Freund's adjuvant-oil induces a T cell-mediated inflammatory joint disease in DA rats. Susceptibility genes for oil-induced arthritis (OIA) are located both within and outside the major histocompatibility complex (MHC, Oia1). We have searched for disease-linked non-MHC loci in an F2 intercross between DA rats and MHC-identical but arthritis-resistant LEW.1AV1 rats. A...

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Identifiers

PMID: 9600974
DOI: 10.1073/pnas.95.11.6383
PMCID: PMC27729

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