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Article

Crystallographic comparison of the estrogen and progesterone receptor’s ligand binding domains

26 May 1998

Abstract excerpt

The 2.8-A crystal structure of the complex formed by estradiol and the human estrogen receptor-alpha ligand binding domain (hERalphaLBD) is described and compared with the recently reported structure of the progesterone complex of the human progesterone receptor ligand binding domain, as well as with similar structures of steroid/nuclear receptor LBDs solved elsewhere. The hormone-bound hERalphaLBD forms a...

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PMID: 9600906
DOI: 10.1073/pnas.95.11.5998

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