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Article

Met909 plays a key role in the activation of the progesterone receptor and also in the high potency of 13-ethyl progestins.

Molecular pharmacology - 1 Jun 2009

Petit-Topin Isabelle, Turque Nathalie, Fagart Jérôme, Fay Michel, Ulmann André, Gainer Erin, Rafestin-Oblin Marie-Edith

Abstract excerpt

Many progestins have been developed for use in contraception, menopausal hormone therapy, and treatment of gynecological diseases. They are derived from either progesterone or testosterone, and they act by binding to the progesterone receptor (PR), a hormone-inducible transcription factor belonging to the nuclear receptor superfamily. Unlike mineralocorticoid, glucocorticoid, and androgen receptors, the...

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Source

Identifiers

PMID: 19289570
DOI: 10.1124/mol.108.054312

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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