Article
Hypervariable minisatellite DNA is a hotspot for homologous recombination in human cells.
Cell - 12 Jan 1990
Wahls W P, Wallace L J, Moore P D
Abstract excerpt
Hypervariable minisatellite DNA sequences are short tandemly repeated sequences that are present throughout the human genome and are implicated to enhance recombination. We have constructed a consensus hypervariable minisatellite sequence and analyzed its effect on homologous recombination in human cells in culture. The consensus sequence d(AGAGGTGGGCAGGTGG)6.5 is shown to stimulate homologous recombination up to...
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