Article
Hypervariable minisatellite DNA is a hotspot for homologous recombination in human cells.
Cell - 12 Jan 1990
Wahls W P, Wallace L J, Moore P D
Abstract excerpt
Hypervariable minisatellite DNA sequences are short tandemly repeated sequences that are present throughout the human genome and are implicated to enhance recombination. We have constructed a consensus hypervariable minisatellite sequence and analyzed its effect on homologous recombination in hum...
Topics
- Animals
- Base Sequence
- Cell Fusion
- Cell Line
- DNA, Satellite
- Genetic Variation
- Humans
- Models, Genetic
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Plasmids
- Polymerase Chain Reaction
- Recombination, Genetic
- Repetitive Sequences, Nucleic Acid
- Transfection
- Urinary Bladder Neoplasms