Article
Genetic alterations of mixed hyperplastic adenomatous polyps in the colon and rectum.
Japanese journal of cancer research : Gann - 1 Mar 1998
Uchida H, Ando H, Maruyama K, Kobayashi H, Toda H, Ogawa H, Ozawa T, Matsuda Y, Sugimura H, Kanno T, Baba S
Abstract excerpt
Some mixed hyperplastic adenomatous polyps (MHAPs) contain dysplastic lesions or even carcinomas. These polyps are considered to be different from ordinary hyperplastic polyps and may have a preneoplastic potential. We investigated APC and K-ras mutations in MHAPs of the colon and rectum, and also in colorectal adenomas and hyperplastic polyps to identify molecular differences between MHAPs, adenomas and...
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