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Detection of JC virus DNA in cerebrospinal fluid from multiple sclerosis patients

1 Apr 1998

Abstract excerpt

JC virus (JCV), the causative agent of progressive multifocal leukoencephalopathy (PML), has been proposed as a possible aetiopathogenic factor in multiple sclerosis (MS). We performed a study to search the LT region of JCV genome by nested PCR in cerebrospinal fluid (CSF), peripheral blood mononuclear cell (PBMC) and urine samples collected from 121 MS patients, 24 patients with other neurological disorders...

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PMID: 9599333
DOI: 10.1177/135245859800400202

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