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Article

Frequency and large T (LT) sequence of JC polyomavirus DNA in oligodendrocytes, astrocytes and granular cells in non-PML brain.

Brain pathology (Zurich, Switzerland) - 1 May 2012

Bayliss Julianne, Karasoulos Tanja, McLean Catriona A

Abstract excerpt

Progressive multifocal leukoencephalopathy (PML) and JCV granular cell neuronopathy occur secondary to JCV polyomavirus (JCV) infection of oligodendrocytes and cerebellar granular cell neurons (CGNs) during immunosuppression. Pure populations of astrocytes, oligodendrocytes, CGNs and microglia from frontal cortex and cerebellum of 17 non-PML patients (9 immunocompetent; 8 immunosuppressed) were isolated by laser...

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Share to Antigens, Viral, Tumor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukoencephalopathy, Progressive Multifocal

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Source

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Identifiers

PMID: 21951346
DOI: 10.1111/j.1750-3639.2011.00538.x
PMCID: PMC8057671

Genes

PML
CGN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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