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Article

GRAFT-VERSUS-HOST-DISEASE-ASSOCIATED THYMIC DAMAGE RESULTS IN THE APPEARANCE OF T CELL CLONES WITH ANTI-HOST REACTIVITY1

1 Feb 2000

Abstract excerpt

BACKGROUND: We studied whether T-cell clones, which appear in the periphery as a result of the failure of thymic negative selection during graft-versus-host disease (GVHD), have any in vivo anti-host reactivity and can cause GVHD in an adoptive transfer model. METHODS: We performed our studies in a murine model (B10.BR into CBA/J) for allogeneic bone marrow transplantation with major histocompatibility...

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Identifiers

PMID: 10706060
DOI: 10.1097/00007890-200002150-00026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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