Article
Lack of interaction of apolipoprotein E phenotype with the lipoprotein response to lovastatin or gemfibrozil in patients with primary hypercholesterolemia.
Metabolism: clinical and experimental - 1 May 1998
Sanllehy C, Casals E, Rodriguez-Villar C, Zambón D, Ojuel J, Ballesta A M, Ros E
Abstract excerpt
The magnitude of serum lipid changes in response to hypolipidemic drugs varies considerably between individuals. These differences may be due to interactions between genetic and environmental factors that effect drug bioavailability or the capacity of the lipid-regulating enzyme and receptor targets to be affected. The apolipoprotein E (apoE) gene locus has been examined in this regard, but reports are...
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