Article
Effect of apolipoprotein E genotypes on the efficacy of ezetimibe monotherapy in patients with statin induced adverse effects.
International journal of clinical pharmacology and therapeutics - 1 Sept 2013
Harangi Mariann, Seres Ildikó, Balogh István, Köbling Tamás, Harangi János, Varga József, Márk László, Paragh György
Abstract excerpt
OBJECTIVE: The aim of this study was to clarify the effect of Apolipoprotein E (ApoE) polymorphism on the efficacy of cholesterol absorption inhibitor ezetimibe monotherapy on lipid parameters. METHODS: 63 hyperlipidemic patients with statin induced adverse effects were involved in the study. We examined the effect of 10 mg/day ezetimibe treatment on lipid levels after 3, 6 and 12 months of treatment in patients...
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