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Article

Haplotype mapping of a major quantitative-trait locus for fetal hemoglobin production, on chromosome 6q23.

American journal of human genetics - 1 Jun 1998

Garner C, Mitchell J, Hatzis T, Reittie J, Farrall M, Thein S L

Abstract excerpt

Fetal hemoglobin (Hb F) and fetal cell (FC) levels in adults show considerable variation and are influenced by several genetic variants; the major determinants appear to be unlinked to the beta-globin gene cluster. Recently, a trans-acting locus controlling Hb F and FC production has been mapped...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 6
Female
Fetal Hemoglobin
Genetic Linkage
Genotype
Haplotypes
Humans
Male
Microsatellite Repeats
Pedigree
Quantitative Trait, Heritable

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9585587
DOI: 10.1086/301859
PMCID: PMC1377138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9585587-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Haplotype mapping of a major quantitative-trait locus for fetal hemoglobin production, on chromosome 6q23.PMID 9585587Read ↗

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