Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Haplotype mapping of a major quantitative-trait locus for fetal hemoglobin production, on chromosome 6q23.

American journal of human genetics - 1 Jun 1998

Garner C, Mitchell J, Hatzis T, Reittie J, Farrall M, Thein S L

Abstract excerpt

Fetal hemoglobin (Hb F) and fetal cell (FC) levels in adults show considerable variation and are influenced by several genetic variants; the major determinants appear to be unlinked to the beta-globin gene cluster. Recently, a trans-acting locus controlling Hb F and FC production has been mapped to chromosome 6q23 in an Asian Indian kindred that includes individuals with heterocellular hereditary persistence of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 6

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Genotype

Share to Haplotypes

Share to Microsatellite Repeats

Share to Pedigree

Share to Quantitative Trait, Heritable

Source

Open in PubMed Open full text

Identifiers

PMID: 9585587
DOI: 10.1086/301859
PMCID: PMC1377138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Haplotype mapping of a major quantitative-trait locus for fetal hemoglobin production, on chromosome 6q23.PMID 9585587Read ↗

Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults.Semantic proximity Read ↗

Control of fetal hemoglobin: new insights emerging from genomics and clinical implications.Semantic proximity Read ↗

The HBS1L-MYB intergenic region on chromosome 6q23 is a quantitative trait locus controlling fetal haemoglobin level in carriers of β-thalassaemiaSemantic proximity Read ↗

[Progress on genes related to fetal hemoglobin quantitative trait].Semantic proximity Read ↗

Genetic Polymorphisms Associated with Fetal Hemoglobin (HbF) Levels and F-Cell Numbers: A Systematic Review of Genome-Wide Association Studies.Semantic proximity Read ↗

Discovering the genetics underlying foetal haemoglobin production in adultsSemantic proximity Read ↗

Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients.Semantic proximity Read ↗

Genetic architecture of hemoglobin F controlSemantic proximity Read ↗

Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation.Semantic proximity Read ↗

Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients.Semantic proximity Read ↗

Evidence of genetic interaction between the beta-globin complex and chromosome 8q in the expression of fetal hemoglobin.Semantic proximity Read ↗

Genetics of Hb F/F cell variance in adults and heterocellular hereditary persistence of fetal hemoglobin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.