Article
Role of alphaII(b)beta3 integrin in prostate cancer metastasis.
The Prostate - 15 May 1998
Trikha M, Raso E, Cai Y, Fazakas Z, Paku S, Porter A T, Timar J, Honn K V
Abstract excerpt
BACKGROUND: Integrins participate in cell-cell and cell-matrix interactions. In this study we determined whether alphaII(b)beta3 integrin is involved in metastasis of human prostate adenocarcinoma cells. METHODS: Prostate adenocarcinoma PC-3 and DU-145 cell lines express alphaII(b)beta3. Northern blotting, 5'-RACE, and immunofluorescent localization confirmed expression of alphaIIb integrin in prostate...
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