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Article

Expression, subcellular localization and putative function of platelet-type 12-lipoxygenase in human prostate cancer cell lines of different metastatic potential.

International journal of cancer - 1 Jul 2000

Timár J, Rásó E, Döme B, Li L, Grignon D, Nie D, Honn K V, Hagmann W

Abstract excerpt

The involvement of 12-lipoxygenase (12-LOX) expression and function in tumor metastasis has been demonstrated in several murine tumor cell lines. In addition, 12-LOX expression was detected in human prostatic tumors and correlated to the clinical stage of disease. Here we provide data that human prostate cancer cell lines express the platelet-type isoform of 12-LOX at both the mRNA and protein levels, and...

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Source

Identifiers

PMID: 10861450
DOI: 10.1002/1097-0215(20000701)87:1<37::aid-ijc6>3.0.co;2-l

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LOX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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