Article
CBFa(AML/PEBP2)-related elements in the TGF-beta type I receptor promoter and expression with osteoblast differentiation.
Journal of cellular biochemistry - 1 Jun 1998
Ji C, Casinghino S, Chang D J, Chen Y, Javed A, Ito Y, Hiebert S W, Lian J B, Stein G S, McCarthy T L, Centrella M
Abstract excerpt
Organization of the transforming growth factor-beta (TGF-beta) type I receptor (TRI) promoter predicts constitutive transcription, although its activity increases with differentiation status in cultured osteoblasts. Several sequences in the rat TRI promoter comprise cis-acting elements for CBFa (AML/PEBP2alpha) transcription factors. By gel mobility shift and immunological analyses, a principal osteoblast-derived...
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